Present work describes simple, accurate, precise and reproducible RP-HPLC method for estimation of tadalafil from the pharmaceutical formulations using RP-C18. Acetonitrile: water was used as mobile phase at a flow rate of 1.2ml/min in the ratio of 50:50 and the detection wavelength was 284nm the accuracy of the method was found to be 98-101% and RSD was found to be less than 2% indicating high degree of accuracy, precision for the proposed HPLC method.
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